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TOP - May 2017, Vol 10, No 2

Project Aims to Prevent Future Infusion-Related Reactions
An infusion-related reaction documentation tool and grading system and its integration into the electronic health record (EHR) is expected to better identify patients at risk for future reactions, and improve communication among oncology team members. Read More ›

Managing Immune-Related Toxicities in Patients with Lung Cancer
Immune-related toxicities in patients with NSCLC can be traced back to the mechanism of action of immune checkpoint inhibitors. Read More ›

A Conversation with Patrick J. Medina, PharmD, BCOP
Patrick J. Medina, PharmD, BCOP, is Professor of Clinical and Administrative Sciences at the University of Oklahoma College of Pharmacy in Tulsa. Read More ›

Real-world experience at the University of Texas M.D. Anderson Cancer Center, Houston, showed that the most frequent immune-related adverse events leading to emergency department visits for patients treated with immune checkpoint inhibitors were diarrhea, colitis, pneumonitis, and dermatitis. Read More ›

The current practice in the treatment of advanced kidney cancer and some other cancers is to continue treatment with immune checkpoint inhibitors until disease progression, and sometimes even longer. Read More ›

Compliance with orders for granulocyte colony-stimulating factors (G-CSFs) is suboptimal, and inadequate prophylaxis was directly tied to hospital admissions, according to results of a recent clinical trial from the University of Pennsylvania Health System. Read More ›

  • Venetoclax plus Rituximab Improves Outcomes in Chronic Lymphocytic Leukemia
  • Lay Navigation Reduces Medicare Costs, Resource Utilization
  • Adding Antiandrogen Therapy Improves Survival in Recurrent Prostate Cancer
Read More ›

A pharmacist-led outreach program at Magellan Rx Management improved adherence to tyrosine kinase inhibitors (TKIs), and compliance with polymerase chain reaction (PCR) testing in patients with chronic myeloid leukemia (CML). Read More ›

By improving chemotherapy-induced peripheral neuropathy (CIPN), administration of duloxetine may enable patients with advanced pancreatic cancer to continue their treatment regimen of gemcitabine plus nab-paclitaxel. Read More ›

Durability of benefit (ie, the possibility for sustained remission in patients with previously incurable disease) is already one of the hallmarks of immunotherapy. According to a recent statistical analysis, however, this durability even exceeded expectations. Read More ›

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