Quick Quiz: Prostate Cancer

Page 1 of 7: Prostate Cancer

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Aside from nonmelanoma skin cancer, prostate cancer is the most common cancer diagnosed among men in the United States and the second leading cause of death in American men.1-3 Most prostate cancers are adenocarcinomas, which begin in the gland cells (the cells that make secretions).1 In rare cases, other types of cancer develop in the prostate, including small-cell carcinomas, transitional-cell carcinomas, neuroendocrine tumors, and sarcomas.1 According to the American Cancer Society, approximately 268,490 men will be diagnosed with prostate cancer in the United States, and approximately 34,500 men will die from the disease.1 How much do you know about prostate cancer?

Approximately 1 in 8 men will be diagnosed with prostate cancer during their lifetime.1 The disease is more likely to be diagnosed in older men and non-Hispanic black men.1 Approximately 60% of diagnoses are in men aged ≥65 years, with the average age at diagnosis being 66 years.1-3 The number of new cases diagnosed in black men is 73% higher than the number of new cases diagnosed in white men, and approximately 37.9 non-Hispanic black men per 100,000 persons will die from the disease.2 Incidence rates of prostate cancer declined in the late 2000s and 2010s because of new screening guidelines that resulted in less prostate-specific antigen (PSA) testing, but rates for advanced-stage prostate cancer rose by 4% to 6% each year from 2014 to 2018.3 In 2018, the US Preventive Services Task Force made recommendations that PSA screenings should include men aged 55 to 69 years, those with average or increased risk for prostate cancer, African-American men, and those with a family history of the disease.4 The 5-year overall survival rate for prostate cancer for all stages combined is 98%; >99% for localized disease, >99% for regional disease, and 31% for distant disease.1,3 Public awareness of effective strategies for preventing, diagnosing, and treating prostate cancer needs to be a priority to reduce the morbidity and mortality associated with the disease.