Lynch Syndrome

In a genomic study of more than 15,000 tumor samples, 16% of individuals with MSI-H tumors were later found to have Lynch syndrome. Zsofia Kinga Stadler, MD, Clinic Director, Clinical Genetics Service, Memorial Sloan Kettering Cancer Center, New York City, presented the results at a press briefing at ASCO 2018.
The novel drug sacituzumab govitecan is showing significant promise in HER2-negative breast cancers. “The benefit was durable, with an estimated medical duration of response of 7.4 months,” reported Aditya Bardia, MD, MPH.

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